Insulin is invented back 100 years and not a single insulin capsule or tablet is available in the market because bare insulin gets degrade into intestine.
We innovators developed a platform technology to solve the age-old problem of oral protein therapeutics and reduced the pain from diabetes patients' life. We inventors worked on the challenge and developed a robust technology to protect the insulin from gastric pH and enzyme. The invention is going to help millions of diabetes patients around the world by providing painless and cost-effective therapy.
It could encapsulate multiple protein therapeutics like antibodies, mRNA, GLP1 in an oral capsule form.
Insulin deficiency causes a disease called diabetes mellitus and administration of exogenous insulin is used to control this disease. The complications of uncontrolled diabetes include blindness, kidney failure, stroke, neuropathy & amputations. It's been recorded by WHO that 422 million people have diabetes in the world which lead to 4.9 million deaths in 2014. Every year ~ 90,000 children below the age of 15 are developing type 1 diabetes in the world and they need to take 2-4 insulin injections in a day to survive.
Department of Chemical Engineering,
Indian Institute of Technology Bombay
Serial Entrepreneur: S2, Calyx therapeutics
San Francisco, California