Insulin Capsule: A LIFE-CHANGER FOR DIABETIC

Problem: Insulin Injections

Insulin is invented back 100 years and not a single insulin capsule or tablet is available in the market because bare insulin gets degrade into intestine.

Solution: Insulin Capsule

We innovators developed a platform technology to encapsulate protein therapeutics in a coating agent to be taken orally. This will reduce the pain from life of diabetics. We inventors worked on the challenge and developed a robust technology to protect the insulin from gastric pH and enzyme. The invention is going to help millions of diabetes patients around the world by providing painless and cost-effective therapy.

Universal Platform Technology

It could encapsulate multiple protein therapeutics like antibodies, mRNA, GLP1 in an oral capsule form.

Unite for Diabetes

Insulin deficiency causes a disease called diabetes mellitus and administration of exogenous insulin is used to control it. The complications of uncontrolled diabetes include blindness, kidney failure, stroke, neuropathy & amputations. It's been recorded by WHO that 422 million people have diabetes in the world which lead to 4.9 million deaths in 2014. Every year ~ 90,000 children below the age of 15 are developing type 1 diabetes in the world and they need to take 2 - 4 insulin injections in a day to survive.

Inventors CredentialS

US Patent 10660941 Granted For Product & Process
Minnesota Microscopy Society, University of Minnesota, USA, 2011 (Best Poster).
Journal of Nanoparticles, 2010 (Article ID 652048).
Langmuir, 2010, Vol. 26 (1), pp. 357-361.
J. Phys. Chem. B, 2009, Vol. 113 (42), pp. 13782-13787.
NSTI NanoTech, The Nanotechnology Conference and Trade Show, Nanotech 2008, Boston, USA.

AIT- Swissnex 2020

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Moise promotes new and cost-effective alternative to insulin injections

Aside from being a renowned businessman, Andrei Octav Moise, businessman and Philanthropist, has been a great advocate of health, especially on diabetes. He has been in the know as to how diabetes has affected a lot of people especially during the rise of more processed food available to the masses.

Diabetes is a health condition where the level of insulin, a hormone produced by the pancreas, is unregulated. Whenever we eat, our body turns most of the food into sugar (glucose) and will release it to the bloodstream. When the level of blood sugar goes up, our brain sends a signal to the pancreas to release insulin. As the main anabolic hormone of the body, insulin helps balance the level of your blood glucose. Insulin aids in storing any excess glucose in your liver once your body detects that you have too much glucose in your bloodstream. And once your blood glucose levels decrease – which happens when you are in between meals, stressed, or need a boost of energy – your stored glucose is released.

When you have diabetes, your body can’t produce enough insulin, or can’t utilize it as needed. Since you do not have enough insulin, excessive glucose stays in your bloodstream. When this is prolonged, this may cause numerous health problems such as vision loss, heart disease, and kidney disease. There are two main types of diabetes, Type 1 and Type 2. Type 1 is an auto-immune disease while Type 2 is when your body has become insulin-resistant.

According to the World Health Organization, around 422 million people worldwide have diabetes, and mostly came from low and middle-income countries. About 1.5 million deaths are directly attributed to diabetes annually. And these numbers have been consistently growing over the past few decades. With this, the WHO has targeted to stop the rise in diabetes and obesity by 2025.

As of date, there still has been no cure for diabetes, but more healthful activities such as consuming healthier food options, being active, and actively losing weight are helpful in decreasing the chances of having diabetes. For those who have Type 1 diabetes, they usually have insulin injected to them several times in a day. Human insulin has been invented for over a 100 years ago, but there are no insulin capsules or tablets available in the market since insulin gets broken down by digestive enzymes before your body gets to use it.

Moise then introduces NeelAgil Technologies from India, one of the leading developers of orally taken insulin therapeutics for treating type 1 diabetes. NeelAgil brings forth the use of Nanotechnology in encapsulating oral insulin which can be taken by insulin-dependent patients. Moise furthers that the company’s aim is to make insulin available in other forms outside of injections through the development of a coating agent that helps avoid insulin getting broken down by enzymes and gastric pH. Through this technology, Moise contends that this invention will help millions of diabetics around the world afford the cost of painless intake of insulin.